This game will take place in Mexico city at altitude. Colt McCoy will be the starting quarterback for the Cardinals in this one. Both teams have offensive weapons but it has been the defenses of both teams that usually show up big. San Francisco has gone under in 6 of their last seven after a straight-up win. Arizona has gone under in 9 of their last 10 Monday night games. Neither team will blow you away with outstanding quarterback play. SF is scoring just 22.0 points per game as they are only scoring touchdowns in 54.8 percent of their red zone trips. I don't expect much from the Cardinals no matter who is under center. The altitude could cause some fatigue later in the game.

Play on the UNDER.