New York Giants at San Francisco 8:15 ET
Giants (+) over 49ers- The 49ers (2-0) streak into their home opener with an NFL-best 12 consecutive regular-season wins. New York avoided traveling coast-to-coast by staying in Arizona after their victory for an extra three nights before trekking to California. Saquon Barkley who led the Giants in rushing (63 yards) and receiving with six receptions last as the Giants rallied last week to beat the Arizona Cardinals 31-28 on Sunday. Still, the Giants are still looking for their first sack and takeaway this season. Giants come to play...take NEW YORK GIANTS!