Iowa State has a good road record when it comes to covering the spread, and their defense is solid. They have had success in the past covering the spread against Cincinnati in four of their last six encounters. Cincinnati are 17-3 straight up at home, but this game will be a tight back and forth game and will be decided close to the buzzer. Iowa State should get the win and cover as they have been strong on the road beating Texas recently and then at home beating TCU soundly. Take the better team.

Best bet: take the points with Iowa State.