The Chargers are 7-3 inside enclosed stadiums this season. The Colts are 3-5-1 inside enclosed stadiums and have lost seven of their last eight. RB Taylor is out so they will struggle to take advantage of the Chargers susceptible run defense. Colts are on their third quarterback in the veteran Foles. He hasn't played a snap this season and will certainly be pressured by Chargers. Must-win for Chargers so lay the points -4.