Home field advantage: Iowa is playing at home at Kinnick Stadium, which can be a tough environment for visiting teams.

Strong run game: Iowa has one of the top rushing attacks in the country, led by Kaleb Johnson who is averaging 154 rushing yards per game. Washington has shown some vulnerability against the run this season.

Defensive strength: Iowa's defense is ranked 22nd in points allowed per game (18.0)1. They could make things difficult for Washington's offense.

Big Ten road struggles: There's a trend of Pac-12 teams that joined the Big Ten struggling on the road against established Big Ten schools. Washington already lost at Rutgers earlier this season.