The Titans have one of the worst offenses in the league and now they are starting Mason Rudolph. He will not have a good time against an aggressive Buffalo defense. The Buffalo offense has been good this year, but the Titans are first in total defense and 1st in passing defense. Buffalo is 25th in passing, so they will need to run the ball a lot and that means the clock will keep churning. Look for a low scoring affair in this one.