This NFC West showdown between the Cardinals and Seahawks leans in favor of Arizona, backed by their strong home-field performance and recent dominance. Playing at State Farm Stadium, the Cardinals have excelled this season, with their defense allowing just 10 points per game in their last three home contests and a stingy 13.5 points per game over their last four games overall.

Offensively, Kyler Murray has been in top form, highlighted by a perfect passer rating in a recent game, and the Cardinals have shown the ability to win decisively, as seen in their earlier 41-10 rout of the Rams. This capacity for big wins adds confidence in their ability to cover or win outright in critical games.

While the Seahawks are riding a three-game winning streak, they’ve been inconsistent throughout the season, and Arizona’s solid betting trends as 2.5-point favorites and better moneyline odds reflect confidence in their recent performances.

Given Arizona's home-field advantage, recent defensive dominance, and Kyler Murray’s exceptional form, the Cardinals are a solid bet on the moneyline in this divisional matchup.