The Denver Broncos have a significant edge playing at Empower Field at Mile High, where their home-field advantage is well-documented. Denver is currently on a three-game winning streak and has been dominant at home, winning four of their last five games. Meanwhile, the Indianapolis Colts face the challenge of traveling to a hostile environment, especially with playoff hopes on the line.

Playoff Stakes Drive Intensity:
This game has major postseason implications. A Broncos win would boost their playoff chances to 89%, while a loss would likely eliminate the Colts, dropping their chances to a mere 7%. This sense of urgency could favor Denver, who has been executing better in high-pressure situations recently.

Defensive Edge and Consistency:
Denver’s defense has been outstanding, ranking second in the league while allowing just 18 points per game. This stout defense is well-positioned to handle the Colts' 18th-ranked offense, which has struggled to consistently put up points. Indianapolis’ defense, ranking 18th as well, may have difficulty containing a Broncos offense averaging 23.5 points per game.

Betting Trends and Historical Performance:
The Broncos are 4-2 at home this season and have consistently covered as favorites, with the betting favorite winning in each of Denver's last nine games. These trends align with their current momentum and matchup advantages.

Conclusion:
With their defensive strength, home-field advantage, and playoff urgency, the Broncos are well-equipped to control this game. Taking Denver -4 appears to be a strong and logical play in this matchup.