Betting Trend: San Francisco is 32-15 SU as a home favorite under HC Kyle Shanahan.

This is a revenge game for the home team after losing two Super Bowls to KC. While the Chiefs are coming off a bye week, the Niners also had extra time to prepare after playing on Thursday Night Football. KC is banged up at the skill positions with Rashee Rice and Isiah Pacheco sidelined, while Jordan Mason has filled in nicely for SF with Christian McCaffrey out. The 49ers' EPA per play (0.103) is much higher than the Chiefs' (0.055).

This is an important game for the 3-3 Niners, who are certainly better than their record suggests. I'm also not sold on the Chiefs being as talented as their 5-0 record implies. Bet on the home team to come out on top on Sunday in California.