Zack Greinke is having a down season especially compared to the monster year he had in 2015. But the prideful Greinke should win here against a foe he has dominated. Greinke pitches better away from Chase Field, too. Arizona is 9-3 in Greinke's 12 road starts. One of those losses was the last time Greinke faced the Padres. That was last month. Greinke left after seven innings leading, 4-2.

Greinke is 7-1 against San Diego in 15 starts with a 1.96 ERA. The Padres are batting .189 against him.

Padres starter Luis Perdomo, a Rule 5 pick forced to stay in the majors or the Padres would lose him, has been very consistently lately. He has a high upside, but is inconsistent and has a 5.68 ERA on the season in 18 starts.

The Diamondbacks are trying to avoid an embarrassing sweep especially since the Padres have now passed them in the standings. San Diego is 7-19 following a victory and three games under .500 at home.