Thanks to Colin Kaepernick the 49ers have shown much improvement during the last three weeks playing the Cardinals, Patriots and Dolphins all tough. Now San Francisco steps way down in class.

Kaepernick has accounted for multiple touchdowns in his last four games. He's a dual threat maybe the best running quarterback in the NFL right now. The Bears are littered with injuries and suspensions everywhere, including inside linebackers minus Jerrell Freeman and Danny Trevathan. That makes Chicago extremely vulnerable to the 49ers' read-option offense.

The Bears aren't going to be able to keep up with the 49ers because of multiple injuries to key offensive linemen and skill position players. Matt Barkley will be making just his second pro start. He's missing several of his best offensive linemen and is throwing to backup receivers, who dropped numerous passes last week. The Bears' two best pass catchers are Alshon Jeffery, who is suspended, and tight end Zach Miller, who's out for the season.

Home-field doesn't matter much when it's the Bears. Chicago has lost 13 of its last 16 at Solider Field going 5-11 ATS.