I can't back the Red Sox at this monster of a lay price when they are pitching James Paxton. But I will say Boston might cover the total just by itself.

That's because the Red Sox draw Connor Seabold and a tired Colorado bullpen that lacks a closer. The Rockies rank 23rd in bullpen ERA at 4.53.
Seabold can take his place among the worst starters in baseball. He has a 5.10 ERA and 1.41 WHIP. It's not just pitching at Coors Field either. Seabold's road ERA is 5.40.

The Red Sox know Seabold well. He was with Boston last season where he had an 11.29 ERA in five starts. The Red Sox rank No. 2 in batting average and OPS when playing at home. They are fourth in home slugging percentage, too. 

I do expect Colorado to chip in to get this total Over. The Rockies have been consistent lately scoring at least four runs in eight of their last 10 games. They are going against James Paxton and a tired Boston bullpen. 

Paxton once was a promising pitcher. Serious injuries have derailed his career. He didn't pitch at all last season. Paxton hadn't been good the two previous seasons in very limited action with ERA's well above 6.00. Paxton has a 3.81 ERA this season.