It's understandable that the Rams sit on top of most people's NFL power ratings. They are strong on both sides of the ball. But I envision the Rams struggling to win this game for a number of reasons.

Sean McVay held his key players out during preseason. The Rams were able to get away with that because their opponents during the first two weeks of the regular season were the Raiders and Cardinals. Both are winless. The Chargers represent a major upgrade.

The Rams are 5-11-1 ATS in their last 17 home games. They don't carry a strong home field advantage especially against this opponent, which also plays now in LA. The Chargers are 15-7-1 ATS in their past 23 road contests.

It is difficult for a team to blow out the Chargers because of Philip Rivers. During their last 18 games, the Chargers have lost by more than a field goal only four times. Rivers is an elite quarterback and is having another excellent season ranking in the top-four in touchdown passes, yards, completion percentage and passer rating.

The Rams have a trio of good wide receivers in Cooper Kupp, Brandin Cooks and Robert Woods. But Keenan Allen is the best wide receiver on the field. He trumps them all. Rivers is especially effective when he has Allen.

Much is being made of Joey Bosa being out. Sure his absence lessens the Chargers' pass rush. But the Chargers still have Melvin Ingram and their secondary, already good, is even better this season with the addition of star rookie safety Derwin James. The Rams are missing one of their key defensive cogs, too, with linebacker Mark Barron expected to sit out a third straight game due to an Achilles injury.

The Rams' kicking game was a huge strength last season because of Greg Zuerlein. However, he's out. So the Rams are going with largely untested backup kicker, Sam Ficken.