Mike Trout, Shohei Ohtani and Justin Upton are all out for the season. Scheduled starting pitcher Jaime Barria has a 6.43 ERA and has lost seven straight decisions.
So am I in my right mind by backing the Angels here? 
Yes. I'll take 1 1/2 runs with the Angels based on the situation, who isn't going to start for Houston today and the horrendous September form of slated Astros starter Wade Miley.
The Astros just played last night at Seattle and were involved in a near no-hitter by Zack Greinke. That was a highly emotional game. They got into LA very early today. Astros manager AJ Hinch said Jose Altuve and George Springer won't be in the starting lineup. He wants to rest them. Carlos Correa also won't be in the lineup either because of a sore back. 
Barria has been bad, but Miley has been worse this month with a mind-blowing 22.09 September ERA giving up 18 runs and 23 hits in only 7 1/3 innings! 
Given these factors, I believe the Angels can hang in.