This matchup has lost much of its star power with no Ben Roethlisberger, Antonio Brown and A.J. Green. It's going to be decided in the trenches - and that's where the Steelers hold a monster edge to go with home field and the mental confidence of having defeated Cincinnati eight straight times.
The Bengals can't run the ball, nor stop the run. That's a very bad combination especially when playing Pittsburgh on the road. The Bengals are last in the NFL in rushing and second from the bottom in run defense.
The Steelers aren't going to be fancy here. They don't need to be. Mason Rudolph should play better in his second NFL start and first at home. He doesn't need to play great, just steady behind a very good offensive line. 
Pittsburgh defense will be fired up. It played very well at San Francisco last week. Rookie Devin Bush gives the Steelers' needed linebacker speed that they haven't had since Ryan Shazier was injured. 
Andy Dalton needs weapons to succeed. Instead he's saddled with a bottom-five offensive line. Bad offensive lines don't travel well. Cincinnati has lost its last seven away matchups.