Daniel Jones has provided a spark to the Giants. Since he replaced Eli Manning, the Giants have gone 2-0. Those victories, though, were against the Buccaneers and Redskins. Now Jones has to step way up in class and face an elite defense, the Vikings. Jones doesn't have much skill position support either with Saquan Barkley out.
The Vikings are in an angry mood after losing to the Bears last week. Don't think for an instant the Giants defense is any good just because they held the impotent Redskins to three points this past Sunday. Kirk Cousins has a history of playing better versus weaker competition. Look for the Vikings to open things up more, too, against the Giants making better use of star wideouts Adam Thielen and Stefan Diggs to go with the dangerous Dalvin Cook in the backfield. 
The Giants are 2-7-1 ATS in their last 10 home games. The Vikings are at least two levels higher than the Giants and should win by double-digits.