Michigan's biggest game of its season always is Ohio State. It's one of the top rivalries in the nation and the best one in the Big Ten. The Wolverines host the Buckeyes next week. That puts them in a dangerous look-ahead spot here against Indiana. It's also a Big Ten Conference sandwich spot for the Wolverines as they just whipped their hated in-state rival, Michigan State, at home this past Saturday.
The Wolverines are 1-4 ATS the last five years in their previous game before Ohio State, including failing to cover the last three seasons in this spot. 
Indiana is much improved. The Hoosiers reached the Top 25 for the first time since 1994 before suffering a 34-27 road loss to Penn State last week. Indiana covered that game and is 6-1 ATS in its last seven games. Michigan hasn't beaten Indiana on the road by more than seven points in its last three visits.
The Hoosiers are averaging 33.3 points. They have the offense to stay within single digits of the Wolverines at home again especially considering Michigan's negative scheduling dynamics.