Zack Godley will lead the Red Sox clown parade of pitchers. It's not going to be pretty. Boston has no pitching and the Yankees have plenty of offense. That offense is starting to flex its muscles as the Yankees have scored 22 runs in their last three games. 
Masahiro Tanaka gets the start for New York. He had a 24.75 ERA versus the Red Sox in eight innings last season. This will be his season debut and he's likely to be on a pitch count. He's been sidelined since getting hit in the head by a line drive on July 4. He has a 5.76 career ERA versus the Red Sox in 21 starts. 
Both offenses should be helped by the wind blowing out to left at 10 mph.