Welcome to the Toilet Bowl. There are three AFC teams who are 0-3. These are two of them. The third is the Texans, who have played at the Chiefs, Ravens and at the Steelers. 
There has been drastic line movement in this matchup with the Jets now the favorite. Much of this line change is due to the Broncos switching quarterbacks going from backup Jeff Driskel to third-stringer Brett Rypien with Drew Lock out. I actually prefer Rypien over Driskel, who is 1-8 as an NFL starter.
Denver is making the long journey to the East Coast. But much of this disadvantage is off-set by this being a night game and fans not being allowed in the stands at MetLife Field. 
The Jets have lost by a combined 57 points, an average of 19 points a game. They've lost to the Bills, battered 49ers and Colts. Denver has two close losses, falling to the Titans by two and to the Steelers on the road by five points. Tennessee and Pittsburgh are each 3-0. 
Even with the Broncos going with a reserve QB, I still rate them superior to the Jets. Denver has the best pass rusher, Bradley Chubb, and more weapons than the Jets with Melvin Gordon, Noah Fant and Jerry Jeudy. The Broncos also might get back talented all-purpose back Phillip Lindsay. 
Sam Darnold has regressed. Perhaps he's seeing ghosts again confused by Adam Gase's complex offense. Gase has a history of getting underachieving performances from players who have thrived when they have gotten away from him. Ryan Tannehill and Kenyan Drake are two prime examples. Darnold might fall into that category, too.  
There's an intangible element here. Speculation is Gase could get fired if the Jets lose this game. Gase is not popular with some of his players. This leaves you to wonder if some Jets are secretly hoping they lose this game in the hopes Gase gets canned? If that were to happen, an interim Jets coach would have 10 days to get ready for the next game so the timing would be good.