Stephen Nover's Colts-Titans Thursday Top Ticket
(NFL) Indianapolis vs. Tennessee,
Point Spread: 1.00 | -110.00 Indianapolis (Away)
Result: Win
If you're judging this matchup just by skill position talent it's no contest. The Titans easily have the three best players in this area with Ryan Tannehill, Derrick Henry and A.J. Brown. 
So why then is this game a pick'em given the Titans' skill position edge and being the home team on a short week? It's because the Colts own the far superior defense, have a better offensive line and have the advantage on special teams. These edges outweigh the Titans' skill position players and put me on the Colts. 
Tremendous credit goes to the Colts for building a defense that ranks No. 1 in total yards giving up 290 yards per game and the third-fewest points at 20 per game. Indy also ranks No. 3 in run defense. Henry hasn't faced the Colts since they upgraded an already good defensive line with DeForest Buckner. I also rate Darius Leonard as the best linebacker in the league. Tannehill is better than Philip Rivers, but he's not an elite quarterback and he won't be that effective with play-action if Henry isn't churning out yards. 
The Bears held the Titans to 4.1 yards per play last Sunday. The Colts' defense is rated higher and their offense is better than the Bears. Indy's run defense surrenders just 3.3 yards per carry. The Titans are without their best offensive lineman, injured left tackle Taylor Lewan. Guard Rodger Saffold might be Tennessee's second-best offensive lineman and he's questionable with a shoulder injury. 
The Colts' offense doesn't scare anyone with Philip Rivers in his NFL dotage. But Indy has produced points when going against non-elite defense such as the Titans averaging 34 points against the Lions, Bengals, Jets and Vikings. Rivers is playing better, producing two of his three highest passer ratings during the past three games with six TD passes during this span. T.Y. Hilton, the Colts' top wide receiver, is expected to play.  
The Titans rank 25th defensively giving up more than 100 yards per game than Indianapolis. Tennessee allows opponents to convert on 55.4 percent of their third downs, which is the worst figure in the NFL. That mark was even higher, but the Titans held the woeful Bears offense to 2-of-15 on third down. 
Then there's the kicking game. It favors Indy.
Colts rookie Rodrigo Blankenship has come through making 17 of 19 field goals. By contrast, Titans place-kicker Stephen Gostkowski has the worst mark in the league for field goal accuracy making just 11 of 18. 
Field position always is important and the Titans won't have their All-Pro punter Brett Kern. He missed his first game since 2009 last week with a wrist injury, ending a string of 180 straight games. Kern has the seventh-highest punting average in the league. Kern also is the Titans' holder on extra points and field goals. 
Ryan Allen replaced Kern against the Bears and did an excellent job punting. But can he do it again? He's not a sure, reliable entity like Kern.