The Patriots' defense is worse than many people thought it was. New England ranks sixth-from-the-bottom in run defense and is going against the No. 1 rushing team in the NFL. New England surrendered 262 passing yards and 3 TD throws to Joe Flacco on Monday, so it can't just stack the line to stop the run against Lamar Jackson. 
The Ravens' defense remains a work-in-progress surrendering 28 points in two of their last three games. Baltimore just lost star pass rusher Calais Campbell to a calf injury. 
There shouldn't be any weather problems either with the forecast calling for temperatures in the 40s with just six mph wind.