The Timberwolves have shown they can't function without their best player, Karl-Anthony Towns. He's going to miss his eighth straight game here due to COVID-19 protocols. Minnesota is 2-14 in its last 16 games and 2-6 ATS in its past eight contests. There's a chance the Timberwolves could be minus their second-best player, D'Angelo Russell, too. He's been dealing with a bruised quad. Russell played in the Timberwolves' 118-94 home loss to the 76ers, but shot just 3-of-11 from the floor in 25 minutes. 
Not only are the Timberwolves a fade in their present state, but the buy sign is on the Cavaliers following their 102-81 loss to the Knicks this past Friday. That was the Cavaliers' second humiliating road loss in a row. They were beaten by 38 points by the Celtics in their previous away game one week ago. 
The Cavaliers want to make a road statement here. They have the perfect patsy in which to make that statement. It helps, too, the Cavaliers finally are at full strength with Darius Garland and Larry Nance Jr. back in the lineup. Andre Drummond leads the NBA in rebounding and Collin Sexton is the league's 16th-leading scorer averaging 24.6 points. The Cavaliers have underrated talent.  
Cleveland has covered during five of its last six visits to Minnesota.