Two young unproven pitchers throwing at hitter-friendly Great American Ball Park with the wind blowing out to left and a single-digit total. Yep that's what we have in this matchup and it spells Over the total for me. 
Pittsburgh is going with JT Brubaker. He was 1-3 with a 5.53 ERA last season as a rookie. The Reds have started the season hot offensively scoring 27 runs, including six homers, in three games against the Cardinals and their respectable pitching staff. 
Cincinnati is pitching rookie Jose De Leon, who pitched six innings last season. De Leon gave up 12 runs on a combined 17 hits/walks during that short span. 
The weather forecast is for wind blowing out to left field at 9-10 mph.