Stephen Nover's MLB Game of the Week
(MLB) Arizona vs. San Diego,
Point Spread: -1.50 | -123.00 San Diego (Home)
Result: Loss
This is one of the biggest mismatches of the season. It's such a mismatch I feel very confident laying 1 1/2 runs with the Padres at home. 
San Diego is that good with eight straight victories and arguably the best and most exciting player in the game, Fernando Tatis. 

Arizona is that bad with 24 straight road losses and 1-20 record during its past 21 overall games. The Diamondbacks are 3-34 in their last 37 games. 
The pitching matchup and bullpen greatly favor the Padres, too. 

Diamondbacks starter Merrill Kelly has a 5.06 ERA. Padres starter Dinelson Lamet has a 2.81 ERA and is rounding into shape pitching deeper into games. He has electrifying stuff.