This is the Jaguars' biggest game of the season. Something Urban Meyer is well aware of. Indications are the Jaguars have had a good week of practice despite the distractions of Meyer.

Trevor Lawrence is getting better at protecting the ball. He faces a very weak defense here. Zach Wilson enjoyed success against the Titans last Sunday. So should Lawrence. Tennessee gives up 27.8 points a game. That's just one fewer point per game than the Jaguars allow.

Jacksonville is capable. They led both the Cardinals and Bengals by nine and 14 points before losing.

Given their injury situation, the Titans should not be laying more than a field goal on the road. Maybe the Titans get back A.J. Brown, but they are likely to still be without Julio Jones and underrated punter Brett Kern. Tennessee also is banged-up in its offensive line. The Titans have yielded 17 sacks, most in the NFL entering this week.