Stop worrying about Trey Lance. He'll be fine playing at home without having to deal with a hostile Chicago crowd playing in monsoon-type conditions. He has a solid offensive line, an ace play-caller in Kyle Shanahan and a real weapon with versatile Deebo Samuel. It's an added bonus if George Kittle can play.

Instead fixate on Seattle's situation. The Seahawks are off a huge home Monday night upset win of Denver and Russell Wilson. Even playing their division rivals, the Seahawks are in a dreadful spot traveling on a short week following that emotional victory.

The Seahawks are 4-12 ATS in their last 16 games following a victory - and that was with Wilson. Now their quarterback is Geno Smith. One game doesn't change the fact that Smith is a game-manager with a propensity for turnovers.

Smith isn't helped playing behind one of the worst and most inexperienced offensive lines in the league. The 49ers hold a monster edge in the trenches with their defensive line. The Seahawks were able to protect their two rookie offensive tackles by throwing only 17 times against the Broncos. That's not likely to happen again. Nick Bosa is right there with Aaron Donald as the most disruptive defensive lineman in the NFC.

The 49ers are going to be up for this game after blowing a 10-0 lead against the Bears. They will play with urgency. San Francisco has covered its last four home contests.

Lance's task is made easier by the Seahawks losing their best defensive and most versatile player, safety Jamal Adams.