Stephen Nover's NFL 5-0 Sunday Sweep
(NFL) Tampa Bay vs. San Francisco,
Point Spread: 3.50 | -110.00 Tampa Bay (Away)
Result: Loss
Tom Brady versus Brock Purdy. Yeah, I'll take 3 1/2 with that

The 49ers have become the best defense in the NFL. But they may not have their most disruptive force with Nick Bosa questionable with a hamstring injury.

The Buccaneers aren't too shabby defensively either. They rank fifth in scoring defense giving up 18.3 points a game and have the fourth-most sacks.

Tampa Bay is 14-5-2 ATS during its last 21 December games.

The 49ers have won five in a row since losing to the Chiefs. Miami was their only win against a winning club, though, during this span.