The Jaguars beat the Colts by 10 points opening week despite Indy getting a gift defensive TD. The Colts then defeated the Texans by 11 points in Week 2 in a game that was more lopsided than the final score. Now the Jaguars get the Texans.

The oddsmaker and marketplace are down on Jacksonville, though, because of its poor performance against the Chiefs at home last week.

But now the Jaguars don't have to worry about Patrick Mahomes or Chris Jones. I see a strong bounce-back effort from the Jaguars at home against a depleted Texans squad.

Trevor Lawrence and Calvin Ridley are in for a big game against the Texans, who have a cluster injury problem in their secondary. Out for the Texans are their top cornerback, Derek Stingley, free safety Jalen Pitre and nickel back Tavierre Thomas. Also hurt and out is Denzel Perryman, one of Houston's better linebackers.

Houston also has multiple injuries in its offensive line. They may get star left tackle Laremy Tunsil back from a knee injury, but remain without three other projected opening day offensive line starters.

The Jaguars' defense is underrated. They gave up 14 points to the Colts' offense and held the Chiefs to 17 points. The Jaguars also have five takeaways, bad news for turnover-prone rookie QB C.J. Stroud.