Stephen Nover's NFL Sunday Night Big Ticket
(NFL) NY Giants vs. Buffalo,
Point Spread: 15.00 | -107.00 NY Giants (Away)
Result: Win
I know the Giants are a hard sell even though this is the largest point spread of the season. Daniel Jones is out. So is left tackle Andrew Thomas, the team's best offensive lineman. I don't expect Saquon Barkley to return for this game either.

But the Bills aren't without key injuries either. They will be missing three important defensive players: linebacker Matt Milano, cornerback Tre'Davious White and nose tackle DaQuan Jones.

The Giants have veteran Tyrod Taylor to fill in for Jones. He's a journeyman. But his mobility and experience make him one of the better backup quarterbacks.

There are three other factors as to why the Giants can stay within two TD's.

At 1-4, the Giants are in desperate shape. They really can't take a loss here. The Bills have a division game up next against the Patriots on the road. They don't want to show anything new to Bill Belichick so they'll be as vanilla as possible.

The Bills are returning from London. Any American who has flown to London and back realizes it takes at least a few days to fully get over jet lag. So there is the real possibility of the Bills being flat for this contest.

Then there's the Brian Daboll angle. He was the Bills' popular and effective offensive coordinator before taking the Giants job last year. Daboll doesn't want to be embarrassed on national TV with this being the Sunday night game. I doubt that Sean McDermott and Josh Allen run up a score on their buddy Daboll.