Weather factors here. There is more than a 90 percent chance of rain in Seattle with the wind blowing at 10-to-15 miles per hour. 

Couple that with D.K. Metcalf likely out and Seattle getting defensive reinforced and there should be fewer points scored than expected. 

The Seahawks are more healthy defensively than they have been. Derrick Hall and Boye Mafe are one of the more underrated pass rushing tandems with a combined nine sacks this season. Seattle also traded for tackling machine linebacker Ernest Jones. 

The Bills are on the road for the fourth time in five weeks. This is their longest road trip. Buffalo has become more ground-oriented this season. Seattle just held the Falcons to 14 points in Atlanta this past Sunday. The Falcons had averaged 33.3 points during their previous three games. 

Seattle has a strong defensive brain trust with head coach Mike Macdonald, the mastermind behind Baltimore's defenses, and assistant head coach Leslie Frazier, a defensive-minded coach who was Buffalo's defensive coordinator from 2017-22. Frazier obviously knows Josh Allen and the Bills well. 

Metcalf suffered a sprained MCL in the Seahawks' win against the Falcons. He's the alpha in Seattle's receiving pecking order and the lone deep threat. 

Buffalo gives up the seventh-fewest points per game at 19.4.