Both Louisville Cardinals and NC State Wolfpack are 4-1 SU but just 1-4 ATS on the season. Louisville crushed the Wolfpack 54-13 as a 19-point favorite last season, and I think they'll win and cover this spread with ease.

The Cardinals are coming off a 55-10 rout of Murray State and racked up 676 yards of total offense in that contest. Louisville has outgained its last two opponents by a combined 985 yards while giving up just a combined 230 yards. Reigning Heisman Trophy winner Lamar Jackson was 18-of-26 passing for 249 yard and three touchdowns and added 100 yards and a score on the ground against Murray State. He produced a huge game against the Wolfpack last year with four touchdowns in the first half alone.

NC State won 27-21 at Florida State as a 10.5-point dog in Week 3, but I don't see them keeping up with the Cardinals high-powered offense here.

My CFB Game of the Week is a 10* play on Louisville Cardinals.