The Buffalo Bills held the Texans to 229 yards of total offense at Houston last week, but still lost the game 20-13. They mustered only 229 yards of total offense themselves and average a poor 12.7 points per game for the season.

Here Buffalo will face a Colts side desperate for a win, entering the Week with a poor 1-5 record after four consecutive losses. Offense has not been an issue for the Colts though as they average 25.3 points and 369.2 yards per game on the season. They've averaged a solid 30.7 ppg through their last three games. Indy quarterback Andrew Luck leads the NFL in pass completions, is second with 16 TDs and the Colts rank 10th in the NFL in passing yards per contest.

Buffalo will turn to Derek Anderson under center. The 35 year old veteran was without a job two weeks ago. The last time Anderson started a game was 2016 and he last played in an NFL game last January. The Colts have an excellent pass rush and are tied for third in the NFL with 19 sacks.

I don't see Buffalo keeping up with this explosive Colts offense.

Free pick on Indianapolis Colts.

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