This is a major let down spot for the Tennessee Titans after putting a 34-10 beating on the Patriots last week. They're 16-34-2 ATS in their last 52 games after scoring more than 30 points in their previous game and here the Titans will face AFC South rival Indianapolis which has won three on the bounce and is 16-5-1 ATS in its last 22 home games vs. a team with a winning road record.

The Colts have averaged 36 ppg during their current winning streak. QB Andrew Luck has thrown for 10 touchdowns during that stretch and at least three TD passes in each of his last six outings.

Prior to a couple of losses to the Titans last year, Indy had claimed 11 straight victories over Tennessee. The Colts have covered the spread in six of the last seven when holding home field advantage and that's a trend likely to continue.

10* play on Indianapolis Colts.