The Cincinnati Reds put a 7-1 beating on Detroit in the season opener. I think they'll come through with another big win here in Game 2 of the series on Saturday. Cincinnati right-hander Luis Castillo finished last season with a 15-8 record behind a 3.40 ERA. This will be his first career start against the Tigers, a situation that usually favors the pitcher. As for Detroit, it is expected to be one of the worst teams in the league this season and right-hander Ivan Nova is 5-7 with a 4.24 ERA in 12 career starts versus the Reds.

Reds are 6-2 in their last 8 interleague games as a favorite. Tigers are 13-41 in their last 54 games as a road underdog.

10* play on Cincinnati -1.5.