GAME OF THE WEEK (NCAAF) - TOP RATED BIG 12 MAJOR WAGER
(NCAAF) Iowa State vs. Oklahoma State,
Point Spread: -3.50 | -102.00 Oklahoma State (Home)
Result: Loss
The No. 6 Oklahoma State Cowboys are 3-0 SU on the season and they have covered the spread in back-to-back games after routing Kansas 47-7 on the road last week.

The Cowboys held the Jayhawks to just 12 downs and 193 yards of total offense and the Cowboys have the 7th best total defense in the nation on the season. Granted, they have not really played offensive powerhouses, but I think they'll do a good job slowing down the No. 18 Iowa State Cyclones.

On the offensive side of the ball, OSU quarterback Spencer Sanders is expected to make his first appearance since suffering an ankle injury in the Cowboys' season opener against Tulsa on Sept. 19. If Sanders is not a go, Shane Illingworth has filled in nicely.

10* play on Oklahoma State Cowboys.