White Sox right-hander Lucas Giolito (8-8, 3.98 ERA) is 2-0 with a 2.57 ERA in two starts against the Twins in 2021 and 4-2 with a 3.89 ERA in seven starts at Target Field.

The Twins hand the ball to right-hander Beau Burrows (0-0, 11.00 ERA) who will make his first career start, but as an opener. Rookie left-hander Charlie Barnes is expected to take over early.

Barnes (0-2, 6.23 ERA) allowed five runs on seven hits and a pair of walks in four innings of a 6-5 defeat against the Reds on Wednesday. The White Sox have destroyed left-handers over the last two seasons, and I think the White Sox win this one in a blowout.

10* play on Chicago White Sox -1.5.