The Pirates are averaging an MLB-worst 3.91 runs per game. Cubs' right-hander Kyle Hendricks (14-7, 4.81 ERA) owns a 3.69 ERA in 23 career starts against the Pirates who counter with Roansy Contreras who will make his MLB debut. Contreras has compiled a 2.64 ERA while pitching for Double-A Altoona and Triple-A Indianapolis this season. The reeling Cubs have lost seven straight. Under is 8-3-1 in the last 12 meetings in Pittsburgh.

10* play on UNDER.