The Niners may not be built to blow teams out of the water, but I think they match up well against the Cardinals. Arizona QB Kyler Murray missed last week's game with a hamstring injury, and if he takes the field here he'll be running for his life against the best defense in the NFL. Murray was a limited participant in practice this week, as was backup QB Colt McCoy who led the team to an upset win against the Rams last week. Following that win, I would not be surprised to see the Cards come out flat tonight.

49ers are 15-4 ATS in their last 19 Monday games. Cardinals are 2-9 ATS in their last 11 Monday games.

10* play on San Francisco 49ers.