The set-up: This series features a few interesting match ups on the mound and this is definitely one of them. The visitors hand the ball to Zach Eflin, while the home side goes with Luis Castillo

The pitchers: Eflin is so far 7-2 with a 3.41 ERA. He comes in off an outing to forget, allowing three runs off five hits with three walks in a no-decision to the Dodgers on Monday. Previous to this dud he'd won six of his last seven starts and despite the shaky performance, he still owns a solid 1.15 WHIP and 68:17 K/BB over 71.1 innings. Also note that he's 3-1 with a 3.62 ERA on the road.

Castillo is so far 5-8 with a 5.30 ERA. He most recently gave up one run off four hits over 5.1 innings in a no-decision to the Cardinals on Monday. Castillo has looked better over the last month, but he still owns a poor 2-5, 5.66 ERA record in all "day" games this season.

The pick: Take it for what you will as well, but Cincinnati is a terrible 33-44 (-5.3 units) this year against right-handed starters, while Philadelphia is 45-35 (+9.5 units) against right-handed pitching. I'm banking on Eflin getting the better of Castillo and for the Phillies to take advantage of this favorable matchup. Play on Philadelphia.