The set-up: The Cards come in off a 4-1 home win over the Padres, while the Dodgers rolled to an impressive 12-6 win at Colorado. While Hyun-Jin Ryu has been excellent to start the year, his counterpart Miles Mikolas has been a train wreck.

The pitchers: The Dodgers go with Hyun-Jin Ryu (2-0, 2.08 ERA) who gave up two runs off six hits with five strikeouts and no walks over seven innings in a win over the Giants on Tuesday. Over his first two starts he has 13 punch outs.

The home side counters with Miles Mikolas (0-1, 7.20) who has uncharacteristically struggled to open the season. Over two starts he's given up eight runs off 12 hits. Last year Mikolas was 18-4 with a 2.83 ERA, so clearly he's struggling with command issues or something else right now.

The pick: Take it for what you will as well, but LA has seen the total go "over" in three of four vs. right-handed starters this year, while St. Louis has seen the total go "over" in seven of its last nine home games after holding its previous opponent to one or less runs in a victory. This number is low.

Dodgers/Cards OVER

10* play