Clemson @ Pittsburgh

I like Pittsburgh to keep the foot on the gas in this one. Clemson is 4-2 and 3-1 in the ACC, most recently coming off a tight 17-14 win against Syracuse, unable to cover the large spread.

The Panthers are 5-1 and 2-0 in conference. They most recently beat Virginia Tech 28-7.

DJ Uiagalelei passed for 181 yards and one touchdown in Clemson's win last weekend, but he now faces one of the best defenses he's ever played against.

Pittsburgh has conceded just 35 points in its past three games and it hasn’t allowed more than 100 yards rushing in those contests.

The Panthers are also 5-1 ATS in their last six against the Conference, while the Tigers are just 2-6 ATS in their last eight as a road dog in the +2.5 to +4.5 points range.

I think Pittsburgh quarterback Kenny Pickett is the difference-maker in the end.

Lay the points, the play is on Pittsburgh.