Best Bet: Bills vs Colts
(NFL) Bills (BUF) vs. Colts (IND),
Point Spread: 4.50 | -120.00 Colts (IND) (Home)
Result: Loss
The Colts looked bad on Sunday Night Football, but you can't overreact to one game. Indianapolis has an NFL-best 4-0 ATS at home this season.
The Bills are riding high on a four-game winning streak, but this is a prime spot for a letdown. Buffalo is coming off a home win over division rival Miami and will play the Chiefs at home next week.

2.5% on the Colts to cover