So no Saquan Barkey for the Giants, and that will definitely hurt them as they need to take some pressure off Danny Dimes somehow or this Niners pass rush will absolutely destroy him. They'll need a stand-in for Barkley, who injured his ankle in the victory and needed assistance to reach the sideline after scoring a rushing touchdown and catching a 9-yard TD toss from Jones to help New York erase a 28-7 deficit. Barkley led the Giants in rushing (63 yards) and receiving (six receptions, tied with tight end Darren Waller).

Christian McCaffrey, the NFL's rushing leader (268 yards) by 88 yards through two games, is set to take on a Giants defense being hit for 4.6 yards per carry and 136.5 rushing yards per game. Martindale's inventive fronts, including a two-man line for multiple snaps against the Cardinals, aren't leading to much success or pressure on the quarterback to date.

So you have one team that can run the ball, and the other that likely won't be able to, and a Giants pass rush that cannot create pressure, vs a Niners defense that has 6 sacks in two games.

This has disaster written all over it for the Giants, let's roll with SF tonight.