Major
(NBA) Chicago vs. Philadelphia,
Point Spread: -8.50 | -102.00 Chicago (Away)
Result: Loss
When the road team is rested and the home team is playing back-to-back and three games in four days, the road team is 507-426.

The Sixers have six or seven NBA caliber players and will be as affected as any playing back-to-back. Ugly.

Undefeated home underdogs not laying more than three-points (can also be an underdog, just any situation in which they are not home favorites of three or more) are 3-7 against the spread in such rare situations.