The moneyline did not have enough value, so we are taking 2.5. But going against road teams off a win as an underdog is 403-184 straight up +107.7 on the moneyline including 12-1, +12.9 units this season.

The Colts are without star WR Reggie Wayne, a huge blow. The Colts rank 29th against the run, surrendering an average of 122.3 yards. Now Case Keenum makes his first home start. He is much better than Matt Schaub as this point.

However Schaub is available and could give them a lift if he comes in with new life after his injury.